Intoxicação por Vitamina D Causada por Erro de Fabricação em um Su-plemento de Vitamina D3 Prescrito, Tratada com Sucesso com Ácido Zoledrônico em Baixa Dose

Conteúdo do artigo principal

Murat Mustafa
https://orcid.org/0009-0006-1536-8424
Sonia Alexiadou
https://orcid.org/0000-0001-7952-4277
Stavros Thomaidis
https://orcid.org/0009-0005-9800-1427
Anna Papazoglou
https://orcid.org/0000-0002-6343-7344
Anastasia Grapsa
Elpis Mantadakis
https://orcid.org/0000-0001-7837-9733

Resumo

A arterite de células gigantes (ACG) é a vasculite mais comum acima dos 50 anos de idade. A ACG é uma condição inflamatória que afeta artérias de médio a grande calibre. A ACG é classificada em uma forma craniana (c-ACG) e uma forma extracraniana/de grandes vasos (GV-ACG). O doppler ultrassonográfico da artéria temporal (UDAT) tornou-se o método de imagem de escolha para o diagnóstico rápido da ACG. Os glicocorticoides (GC) permanecem como o tratamento primário da ACG. Relatamos o caso de uma mulher de 79 anos com cefaleia temporal, hemiparesia direita e hipoestesia. Ela apresentava anemia normocítica normocrômica, proteína C reativa (PCR) e velocidade de hemossedimentação (VHS) elevadas. A ressonância cerebral (RC) revelou infartos bi-hemisféricos. Foi diagnosticado acidente vascular cerebral lacunar sensitivo-motor à esquerda. O UDAT revelou halo hipoecoico nas artérias temporais. A c-ACG foi diagnosticada como a etiologia do AVC e tratada com GC, com resolução dos sintomas. O acidente vascular cerebral isquêmico é uma complicação rara na ACG e constitui uma condição com risco de vida. Este caso se destaca pela importância dos GC como terapia eficaz na ACG com envolvimento intracraniano sintomático, melhorando o prognóstico. Na prática clínica diária, o diagnóstico precoce da ACG pode ser desafiador.

Detalhes do artigo

Como Citar
Mustafa, M., Alexiadou, S., Thomaidis, S., Papazoglou, A., Grapsa, A., & Mantadakis, E. (2025). Intoxicação por Vitamina D Causada por Erro de Fabricação em um Su-plemento de Vitamina D3 Prescrito, Tratada com Sucesso com Ácido Zoledrônico em Baixa Dose. Brazilian Journal of Case Reports, 6(1), bjcr112. https://doi.org/10.52600/2763-583X.bjcr.2026.6.1.bjcr112
Seção
Clinical Case Reports
Biografia do Autor

Murat Mustafa, Department of Pediatrics, University General Hospital of Alexandroupolis

Department of Pediatrics, University General Hospital of Alexandroupolis, Thrace, Greece.

Sonia Alexiadou, Department of Pediatrics, University General Hospital of Alexandroupolis

Department of Pediatrics, University General Hospital of Alexandroupolis, Thrace, Greece.

Stavros Thomaidis, Department of Pediatrics, University General Hospital of Alexandroupolis

Department of Pediatrics, University General Hospital of Alexandroupolis, Thrace, Greece.

Anna Papazoglou, Department of Pediatrics, University General Hospital of Alexandroupolis

Department of Pediatrics, University General Hospital of Alexandroupolis, Thrace, Greece.

Anastasia Grapsa, Department of Biopathology and Biochemistry, University General Hospital of Alexandroupolis

Department of Biopathology and Biochemistry, University General Hospital of Alexandroupolis, Thrace, Greece.

Elpis Mantadakis, Department of Pediatrics, University General Hospital of Alexandroupolis

Department of Pediatrics, University General Hospital of Alexandroupolis, Thrace, Greece.

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